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Writer's pictureVicki Hexter

Dermalogica MelanoPro peel System Information

Updated: Nov 26


The Dermalogica Melanopro Peel System is a professional-grade chemical peel that aims to reduce hyperpigmentation and dark spots, and improve skin texture.


The Dermalogica Melanopro is an effective & convenient way to improve pigmentation & skin quality. This peel treats superficial melasma, post acne marks & sun damage with minimal downtime & maximal results. 



The science of Melanopro Peels

  • This peel system can reduce melasma pigmentation & age spots

  • With continued use this peel will markedly improve skin texture 

  • Melanopro has very little downtime & compares favorably with Cosmelan peels

  • Melanopro is a two stage chemical peel

  • Stage one is performed in office

  • Stage two lasts 6 weeks & comprises at home skin care


What it is?

Melanopro Peel System is a clinical-strength peel program that delivers visible results in less than 6 weeks.

This transformative 2-phase regimen works to visibly counteract environmental skin damage – fading dark spots, reducing the appearance of hyperpigmentation, and smoothing skin’s texture to reveal fresh, brighter skin.


Who it’s for?

Melanopro Peel System is an effective treatment regimen for anyone who experiences hyperpigmentation concerns:

  • sun spots

  • scarring

  • melasma

  • dull skin

  • rough texture.

It has been tested on all skin tones.


What’s unique about it?

It is the first 2-phased clinical strength program that safely fades all forms of hyperpigmentation in under 6 weeks.


When is it best to have this treatment?

It is ideal to prescribe Melanopro Peel System in autumn or winter, when most clients receive less sun exposure. It has been extensively tested and is safe on all skin tones and ethnicities.


What types of pigmentation can the Melanopro Peel address?


Melasma Pigmentation

Caused by hormonal changes that can impact melanin production. These changes are often associated with pregnancy or when using birth control, and result in areas of hyperpigmentation that most commonly appear on the forehead, cheeks and upper lip. These dark spots often look like patches or a mask and may also be symmetrical.



MelanoPro is suited for superficial & mixed depth melasma pigmentation. Deep or dermal melasma responds better to microneedling treatments.


Sun Spots

Sun or age spots are related to excess sun exposure over time and considered

the most common form of hyperpigmentation. Generally, they

appear as spots on areas exposed to the sun, like the hands, neck, chest and face.


Age & sun related pigment can be effectively faded with this peel. It can be used on the face, chest & decolletage areas. 

Post Inflammatory Hyperpigmentation

Post-inflammatory hyperpigmentation (PIH) is the result of inflammation or injury to the skin, for example, acne,

deep cuts or burns. PIH may appear differently in varying skin tones.

For example, a low Fitzpatrick client with PIH from breakouts may have

hyperpigmentation that appears pink or red, due to inflammation and

the color of the pheomelanin present in the PIH. The exact same PIH in a melanin-rich skin may appear purple, brown, or black due to the variations of eumelanin present in the PIH. MelanoPro can effectively treatment all types of PIH.


Dull Skin and Sun Damaged Skin

The Melanopro peel is one of the best ways to put life back into aging skin. It improves skin luminosity, reduces uneven skin texture & visibly brightens skin.  








Contraindications for Melanopro:

  • This system is not advised for those with highly sensitive skin or those who have skin conditions such as rosacea, eczema, etc.

  • Not for use on those that have sunburned skin.

  • Not for use on pregnant or breastfeeding women.

  • Not for use on those with active cold sores.

  • Not for use on those with open skin lesions.

  • Not for those currently using Isotretinoin in the past 6 months.

  • Not for those with a history of diabetes.

  • Not for those prone to keloid scars.

  • Not for use on those who have had injectables in the past 14 days.

  • Not for use during active cancer treatment.


Pre treatment advice

These pre-service guidelines are important to follow to achieve the best results from the service.

  • Do not use topical skin care products containing ingredients that may increase skin sensitivity such as retinoids, exfoliants, topical antibiotics, or hydroxy acids one week prior to treatment.

  • Avoid Accutane six months prior to service. Consult with your prescribing physician for guidance.

  • Avoid waxing, depilatory creams, or electrolysis on face five days prior to treatment.

  • Avoid IPL/laser procedures at least two weeks prior to treatment.

  • Avoid unprotected sun exposure or sunburn at least two weeks prior to treatment.

  • Avoid experimenting with new skin care products 2 weeks before treatment.


Patch testing required

Prior to using the Melanopro Peel System. Patch testing is a way to gauge if a client may be contraindicated to treatment & is recommended if-

How the product is patch tested:

  1. A small area behind the ears is cleanse.

  2. A small amount of Day One Peeling Masque is applied behind the ear.

  3. A small amount of Continuous Resurfacing Cream is also applied behind the ear.

During the patch test, you may experience a tingling sensation and/or warmth - this is normal. The creams are kept on the skin for up to 90 minutes and then remove with water. Monitor the area for 24-48 hours and inform the skin therapist of any skin changes. Watch for signs of extreme redness, rash, swelling or hives. If any of these appear, you may not be suitable for the Melanopro Peeling System.



How many sessions will I require to clear my pigment?

Melanopro is a two stage peel

Stage 1 is a in clinic treatment

Stage 2 is a 6 week at home treatment.


When will I see results?

Most patients will see results within a few weeks of treatment. 

Week 1-2; skin will feel smoother. 

Week 3-4; skin will look brighter with less pigment. 

Week 4-6; maximal results will be noticeable. 

*Melanopro is designed to reduce, not completely eliminate pigmentation.







What are the key ingredients of the Melanopro Peel?

Dermalogica has carefully selected key ingredients to optimize pigmentation removal, whilst mimicking the downtime associated with traditional peels. Ingredients are- 

Azelaic Acid acts as a tyrosinase inhibitor, reducing melanin production while gently exfoliating the skin to speed up cell turnover and remove dull surface layers. 

Tranexamic Acid, derived from amino acids, effectively reduces hyperpigmentation by inhibiting an enzyme crucial to melanin production, promoting a more uniform complexion. 

Salicylic Acid (SA), or Beta Hydroxy Acid (BHA), penetrates the skin’s lipid barrier, loosening the bonds between cells to encourage the shedding of dead skin, resulting in smoother, more even-toned skin. 

Glycolic and Lactic Acids, both AHAs, disrupt the cohesion between skin cells to exfoliate the outer layers and also provide moisturizing benefits. 

Retinol, a potent form of Vitamin A, enhances cell turnover and reduces melanin synthesis, leading to a brighter, more even skin tone.

Niacinamide, also known as Vitamin B3, prevents melanin from reaching the skin’s surface by inhibiting the transfer of melanin-containing melanosomes to keratinocytes, reducing dark spots and uneven tone. 

Acetyl Hexapeptide-1, a depigmenting peptide, decreases melanin production and transfer, contributing to a more even complexion.


How does the MelanoPro compare with Cosmelan peels?

Cosmelan & Dermamelan peels have significant downtime, namely 7 to 14 days. These peels work faster but at the expense of prolonged skin inflammation & irritation. 

In contrast the Melanopro peel has only 2-3 days of mild peeling with little to no downtime with simlar results.


Can the Melanopro Peel be customized to different skin types?

MelanoPro peels are suitable for all skin types & can be customised for sensitive skin. 

  • Skin type 1,2 (European, Caucasian): peel time 7 hours

  • Skin type 3,4 (Asia, Middle Eastern): peel time 6 hours

  • Skin type 5,6 (Indian, African): peel time 5 hours


The Process...




Day 1: In clinic treatment peeling masque


Intensive peeling masque to target persistent hyperpigmentation.

Ingredients: 10% Azelaic acid is combined with Salicylic Acid, Tranexamic Acid, Retinol, Niacinamide, and a brightening peptide: Acetyl Hexapeptide-1.

Mode of action: The masque kick-starts intense exfoliation and starts to fade the appearance of hyperpigmentation. Due to its masque texture, it does not dry down and allows for the ingredients to provide continuous benefits.

Application / removal: Applied & left on the skin for 3-7 hours. It is removed at home. 




Continuous Resurfacing Cream


Intensive peeling cream to target pigmentation challenges.

Ingredients: 10% Azelaic Acid is combined with Salicylic Acid, Tranexamic Acid, Glycolic Acid, Lactic Acid, Retinol, Niacinamide, Hexylresorcinol and a brightening peptide: Acetyl Hexapeptide-1.

Mode of action: The cream is applied daily to stimulate continuous exfoliation, brighten skin, smooth texture and reduce the appearance of hyperpigmentation.

Application: 2-3 times per day, following the instructions of the professional skin therapist.





Ultracalming mist

Soothing, hydrating mist to help calm redness and sensitivity. Use post- cleanse and throughout the day to soothe the skin and lock in hydration. Lightweight mist quickly absorbs to support a functioning skin barrier, helping to minimize future flare-ups.

Ingredients: UltraCalming Complex contains Oat and botanicals to help soothe and strengthen skin, and soothing Aloe helps calm while supporting a natural moisture balance in skin

Application: Use as often as needed during the Melanopro Peel System following the instructions of the professional skin therapist.



Frequently ask questions

Apart from tingling and a slight feeling of sunburn, what else can be experienced on their skin?

Skin redness and a slight irritating sensation, tingling and occasional itchiness is the most common effects. If there

is swelling, extreme redness or it is highly uncomfortable, discontinue the peel. The skin usually peels between days 3 and 7.

We have had instances where peeling lasted up to 14 days (about 2 weeks), but it is rare.

What skin treatment would you suggest once home care has been completed?

Once the Day One Peeling Masque is applied in the skin center and you go home do you need to keep the Masque moist through the day?

What do I do if I cannot tolerate the Day One Peeling Masque and need to remove it?

How often can Melanopro Peel System be performed?

Melanopro can safely be performed every six months.

Can Melanopro Peel System be offered during the summer months?

Can I use my usual serums while using the Continuous Resurfacing Cream during the Melanopro treatment?

How do I remove the peel at home?

Have there been any clinical trials for MelanoPro?

What other aspects of skin can the Melanopro peel address?

This peel is one of the most effective skincare products for improving skin texture. The unique combination of skincare acids (AHA & BHA) provides unparalleled exfoliation. The result? Smoother skin with an improvement of textural roughness, in addition to brighter & more radiant skin.



Before and After Photos of MelenoPro







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